NAME
Bio::Tools::Signalp - parser for Signalp output
SYNOPSIS
use Bio::Tools::Signalp;
my $parser = Bio::Tools::Signalp->new(-fh =>$filehandle );
while( my $sp_feat = $parser->next_result ) {
if ($sp_feat->score > 0.9) {
push @likely_sigpep, $sp_feat;
}
}
DESCRIPTION
SignalP
predicts the presence and location of signal peptide cleavage sites in amino acid sequences.
Bio::Tools::Signalp parses the output of SignalP
to provide a Bio::SeqFeature::Generic object describing the signal peptide found, if any. It returns a variety of tags extracted from the NN and HMM analysis. Most importantly, the score()
attribute contains the NN probability of this being a true signal peptide.
FEEDBACK
Mailing Lists
User feedback is an integral part of the evolution of this and other
Bioperl modules. Send your comments and suggestions preferably to
the Bioperl mailing list. Your participation is much appreciated.
bioperl-l@bioperl.org - General discussion
http://bioperl.org/wiki/Mailing_lists - About the mailing lists
Reporting Bugs
Report bugs to the Bioperl bug tracking system to help us keep track of the bugs and their resolution. Bug reports can be submitted va the web:
http://bugzilla.open-bio.org/
AUTHOR
Based on the EnsEMBL module Bio::EnsEMBL::Pipeline::Runnable::Protein::Signalp originally written by Marc Sohrmann (ms2_AT_sanger.ac.uk). Written in BioPipe by Balamurugan Kumarasamy savikalpa_AT_fugu-sg.org. Cared for by the Fugu Informatics team (fuguteam_AT_fugu-sg.org)
CONTRIBUTORS
Torsten Seemann - torsten.seemann AT infotech.monash.edu.au
APPENDIX
The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _
new
Title : new
Usage : my $obj = new Bio::Tools::Signalp();
Function: Builds a new Bio::Tools::Signalp object
Returns : Bio::Tools::Signalp
Args : -fh/-file => $val, # for initing input, see Bio::Root::IO
next_result
Title : next_result
Usage : my $feat = $signalp->next_result
Function: Get the next result set from parser data
Returns : Bio::SeqFeature::Generic
Args : none
_parse_hmm_result
Title : _parse_hmm_result
Usage : $self->_parse_hmm_result(\%feature)
Function: Internal (not to be used directly)
Returns : hash of feature values
Args : hash of more feature values
_create_feature
Title : _create_feature
Usage : $self->create_feature(\%feature)
Function: Internal (not to be used directly)
Returns : hash of feature values
Args : hash of more feature values
_seqname
Title : _seqname
Usage : $self->_seqname($name)
Function: Internal (not to be used directly)
Returns :
Args :
_fact1
Title : _fact1
Usage : $self->fact1($fact1)
Function: Internal (not to be used directly)
Returns :
Args :