NAME

Bio::Tools::Signalp - parser for Signalp output

SYNOPSIS

use Bio::Tools::Signalp;

my $parser = Bio::Tools::Signalp->new(-fh =>$filehandle );

while( my $sp_feat = $parser->next_result ) {
  if ($sp_feat->score > 0.9) {
     push @likely_sigpep, $sp_feat;
  }
}

DESCRIPTION

SignalP predicts the presence and location of signal peptide cleavage sites in amino acid sequences.

Bio::Tools::Signalp parses the output of SignalP to provide a Bio::SeqFeature::Generic object describing the signal peptide found, if any. It returns a variety of tags extracted from the NN and HMM analysis. Most importantly, the score() attribute contains the NN probability of this being a true signal peptide.

FEEDBACK

Mailing Lists

User feedback is an integral part of the evolution of this and other
Bioperl modules. Send your comments and suggestions preferably to
the Bioperl mailing list.  Your participation is much appreciated.

 bioperl-l@bioperl.org                  - General discussion
 http://bioperl.org/wiki/Mailing_lists  - About the mailing lists

Support

Please direct usage questions or support issues to the mailing list:

bioperl-l@bioperl.org

rather than to the module maintainer directly. Many experienced and reponsive experts will be able look at the problem and quickly address it. Please include a thorough description of the problem with code and data examples if at all possible.

Reporting Bugs

Report bugs to the Bioperl bug tracking system to help us keep track of the bugs and their resolution. Bug reports can be submitted va the web:

https://github.com/bioperl/bioperl-live/issues

AUTHOR

# Please direct questions and support issues to bioperl-l@bioperl.org

Based on the EnsEMBL module Bio::EnsEMBL::Pipeline::Runnable::Protein::Signalp originally written by Marc Sohrmann (ms2_AT_sanger.ac.uk). Written in BioPipe by Balamurugan Kumarasamy savikalpa_AT_fugu-sg.org. Cared for by the Fugu Informatics team (fuguteam_AT_fugu-sg.org)

CONTRIBUTORS

Torsten Seemann - torsten.seemann AT infotech.monash.edu.au

APPENDIX

The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _

new

Title   : new
Usage   : my $obj = Bio::Tools::Signalp->new();
Function: Builds a new Bio::Tools::Signalp object
Returns : Bio::Tools::Signalp
Args    : -fh/-file => $val, # for initing input, see Bio::Root::IO

next_result

Title   : next_result
Usage   : my $feat = $signalp->next_result
Function: Get the next result set from parser data
Returns : Bio::SeqFeature::Generic
Args    : none

_parse_hmm_result

Title   : _parse_hmm_result
Usage   : $self->_parse_hmm_result(\%feature)
Function: Internal (not to be used directly)
Returns : hash of feature values
Args    : hash of more feature values

_create_feature

Title   : _create_feature
Usage   : $self->create_feature(\%feature)
Function: Internal (not to be used directly)
Returns : hash of feature values
Args    : hash of more feature values

_seqname

Title   : _seqname
Usage   : $self->_seqname($name)
Function: Internal (not to be used directly)
Returns :
Args    :

_fact1

Title   : _fact1
Usage   : $self->fact1($fact1)
Function: Internal (not to be used directly)
Returns : 
Args    :

cpanm BioPerl

perl -MCPAN -e shell
install BioPerl