/ 
BioPerl-Network-1.006902
River stage zero No dependents
/ Bio::Network::IO::psi25

NAME

Bio::Network::IO::psi25

SYNOPSIS

Do not use this module directly, use Bio::Network::IO:

my $io = Bio::Network::IO->new(-format => 'psi25',
                               -file   => 'data.xml');

my $network = $io->next_network;

DESCRIPTION

PSI MI (Protein Standards Initiative Molecular Interaction) XML is a format to describe protein-protein interactions and interaction networks. This module parses version 2.5 of PSI MI.

Databases

The following databases provide their data as PSI MI XML:

Each of these databases will call PSI format by some different name. for example, PSI MI from DIP comes in files with the suffix "mif" whereas PSI MI from IntAct or MINT has the "xml" suffix.

Documentation for PSI XML can be found at http://www.psidev.info.

Version

This module supports a subset of the fields described in PSI MI version 2.5. (http://www.psidev.info/index.php?q=node/60). The DATA IN THE NODE section below describes which fields are currently parsed into ProteinNet networks.

Notes

See the Bio::Network::IO::psi_xml page in the Bioperl Wiki (http://bioperl.open-bio.org/wiki/Bio::Network::IO::psi_xml) for notes on PSI XML from various databases.

When using this parser recall that some PSI MI fields, or classes, are populated by values taken from an ontology created for the PSI MI format. This ontology is an OBO ontology and can be browsed at http://www.ebi.ac.uk/ontology-lookup/browse.do?ontName=MI.

METHODS

The naming system is analagous to the SeqIO system, although usually next_network() will be called only once per file.

DATA IN THE NODE

The Node (protein or protein complex) is roughly equivalent to the PSI MI interactor (entrySet/entry/interactorList/interactor). The following are subclasses of interactor whose values are accessible through the Node object.

DATA NOT YET AVAILABLE

The following are subclasses of interactor whose values are currently not accessible through the Node object.

INTERACTION DATA

The Interaction object is roughly equivalent to the PSI MI interaction (entrySet/entry/interactionList/interaction) and experimentDescription (entrySet/entry/experimentList/experimentDescription). The following are subclasses of interaction and experimentDescription whose values are NOT yet accessible through the Interaction object.

FEEDBACK

Mailing Lists

User feedback is an integral part of the evolution of this and other Bioperl modules. Send your comments and suggestions preferably to one of the Bioperl mailing lists. Your participation is much appreciated.

bioperl-l@bioperl.org                  - General discussion
http://bioperl.org/wiki/Mailing_lists  - About the mailing lists

Support

Please direct usage questions or support issues to the mailing list:

bioperl-l@bioperl.org

rather than to the module maintainer directly. Many experienced and reponsive experts will be able look at the problem and quickly address it. Please include a thorough description of the problem with code and data examples if at all possible.

Reporting Bugs

Report bugs to the Bioperl bug tracking system to help us keep track the bugs and their resolution. Bug reports can be submitted via the web:

http://bugzilla.open-bio.org/

AUTHORS

Brian Osborne bosborne at alum.mit.edu

next_network

Name       : next_network
Purpose    : Constructs a protein interaction graph from PSI XML data
Usage      : my $net = $io->next_network()
Arguments  :
Returns    : A Bio::Network::ProteinNet object

_addInteractor

Name      : _addInteractor
Purpose   : Parses protein information into Bio::Seq::RichSeq objects
Returns   :
Usage     : Internally called by next_network()
Arguments : None
Notes     : Interactors without organism data get their Bio::Species
            fields set to -1

_addInteraction

Name     : _addInteraction
Purpose  : Adds a new Interaction to a graph
Usage    : Do not call, called internally by next_network()
Returns  :
Notes    : All interactions are made of 2 nodes - if there are more
           or less than 2 then no Interaction object is created